MediAI

  Gorlin-Goltz Syndrome: A Multisystem Disorder Unveiled Through Jaw and Pelvic Pain in a 25-Year-Old Woman Introduction Gorlin-Goltz syndrome (GGS), also known as nevoid basal cell carcinoma syndrome (NBCCS), is a rare autosomal dominant condition with multisystem involvement. Early clinical presentation may include odontogenic keratocysts (OKCs), basal cell carcinomas (BCCs), skeletal anomalies, and ovarian fibromas. This column explores a clinical case of a 25-year-old female presenting with jaw and pelvic pain, ultimately diagnosed with Gorlin-Goltz syndrome, and reviews the underlying pathology, clinical features, diagnostic imaging, and management strategies of the syndrome. Clinical Case Summary A 25-year-old woman presented with chronic jaw and pelvic pain. Her medical history revealed prior surgical treatment for jaw pain, recurrent skin neoplasms later diagnosed as basal cell carcinomas, and a history of medulloblastoma. She also underwent a partial cystectomy six y...

Large-Bowel Obstruction Induced by Hereditary Angioedema: A Case-Based Scientific Review Keywords : hereditary angioedema, large-bowel obstruction, C1 esterase inhibitor deficiency, abdominal angioedema, gastrointestinal edema, complement system disorder, bowel ischemia, bowel wall thickening Abstract Hereditary angioedema (HAE) is a rare, life-threatening genetic disorder characterized by episodes of severe swelling due to C1 esterase inhibitor (C1-INH) deficiency. While common manifestations include cutaneous and oropharyngeal edema, gastrointestinal involvement is frequently underrecognized. This article presents a case of large-bowel obstruction due to bowel wall edema secondary to HAE and discusses the underlying etiology, clinical presentation, imaging findings, and management strategies, with emphasis on the need for early recognition and appropriate long-term prophylaxis. Introduction Large-bowel obstruction (LBO) represents a surgical emergency with multiple potential e...

  Chronic Eosinophilic Pneumonia Neumonía eosinofílica crónica 만성 호산구성 폐렴 Keywords: chronic eosinophilic pneumonia, peripheral airspace opacities, photographic negative, eosinophilia, prednisone, CT scan, allergic asthma, corticosteroid response Introduction Chronic eosinophilic pneumonia (CEP) is a rare but distinct form of idiopathic interstitial lung disease characterized by prominent pulmonary and peripheral eosinophilic infiltration.  Often affecting middle-aged women with a history of asthma or atopy, it presents insidiously with systemic symptoms that mimic more common pulmonary infections or malignancies.  A hallmark radiological feature, described as the “imaging negative of pulmonary edema,” provides a vital diagnostic clue and has been consistently associated with CEP.  This case-based discussion outlines the pathogenesis, clinical and imaging characteristics, diagnosis, and treatment of CEP. Case Summary A 54-year-old woman with known allergic rhi...

  Understanding Xanthogranulomatous Cholecystitis: A Rare Mimicker of Gallbladder Carcinoma Comprensión de la colecistitis xantogranulomatosa: una rara réplica del carcinoma de vesícula biliar 담낭암의 희귀한 유사 질환인 황색육아종성 담낭염 이해 Keywords:  xanthogranulomatous cholecystitis , RUQ pain CT , gallbladder wall thickening , gallbladder cancer mimic , intramural cystic spaces , fat stranding gallbladder , xanthogranulomatous inflammation , cholecystectomy findings , rare gallbladder diseases , radiology gallbladder diagnosis Introduction Xanthogranulomatous cholecystitis (XGC) is a rare, chronic inflammatory condition of the gallbladder that often mimics gallbladder carcinoma on imaging. This diagnostic dilemma necessitates careful radiological interpretation and often surgical confirmation. In this column, we delve into the intricacies of XGC through a compelling case of a 55-year-old male presenting with intermittent right upper quadrant (RUQ) pain. This post aims to serve both as a...

  Purulent Pericarditis: A Rare but Fatal Cardiac Emergency – Case Study and Review Pericarditis purulenta: una emergencia cardíaca rara pero mortal – Estudio de caso y revisión 화농성 심낭염: 드물지만 치명적인 심장 응급 상황 – 사례 연구 및 검토 Keywords: Purulent pericarditis, pericardial empyema, MRSA pericarditis, chest CT, cardiac tamponade, infectious pericarditis, pericardial effusion Introduction Purulent pericarditis is an exceedingly rare but life-threatening infection of the pericardial sac, accounting for less than 1% of all cases of pericarditis. This blog post presents a detailed case study of a 42-year-old female with purulent pericarditis associated with methicillin-resistant Staphylococcus aureus (MRSA), highlighting imaging findings, differential diagnosis, management, and clinical course. This comprehensive analysis is intended for medical professionals, radiologists, and students aiming for a deeper understanding of this high-mortality condition. Case Presentation History and Clin...