Ewing Sarcoma: Pathophysiology, Imaging Features, Diagnosis, and Treatment – A Comprehensive Review
Ewing sarcoma is one of the most aggressive and clinically challenging malignant bone tumors affecting children and young adults. This column provides a comprehensive review of Ewing sarcoma , focusing on its pathophysiology, epidemiology, clinical presentation, imaging features, differential diagnosis, treatment, and prognosis , supported by leading literature. The case study and imaging examples included here will serve as both a clinical guide and an educational resource for medical students, radiology residents, and oncology specialists. Case Presentation A 13-year-old girl presented with several months of left chest wall pain . She underwent chest radiography and CT imaging. The findings are discussed below. History and Radiography Patient : 13-year-old female Symptom : Persistent left chest wall pain Figure 1. Chest Radiograph (P-A View). Interpretation: Expansile lesion involving the anterior portion of the 4th left rib. No evidence of pneumothorax or significant p...