Testicular Epidermoid Cyst: Imaging Diagnosis, Differential Diagnosis, and Evidence-Based Management
Introduction Testicular epidermoid cyst is a rare, benign intratesticular lesion that accounts for approximately 1–2% of all testicular tumors . Despite its benign nature, it represents a critical diagnostic challenge because its imaging appearance may overlap with malignant germ cell tumors. An accurate diagnosis is essential to avoid unnecessary radical orchiectomy , particularly in young men of reproductive age. With the evolution of high-resolution scrotal ultrasound and multiparametric MRI , testicular epidermoid cyst has become one of the few testicular lesions that can be confidently diagnosed preoperatively . This column provides a comprehensive, evidence-based review of testicular epidermoid cyst, focusing on pathophysiology, epidemiology, clinical presentation, imaging features, differential diagnosis, diagnosis, treatment, and prognosis , based on the most authoritative and recent global literature . Pathophysiology A testicular epidermoid cyst is a ...