MediAI

Introduction Liver cirrhosis represents the terminal stage of chronic liver disease and remains a significant cause of morbidity and mortality worldwide. This blog column aims to provide a globally optimized, expert-level overview of liver cirrhosis, integrating the latest evidence-based practices.  Case A 72-year-old female presented with lower extremity edema and had a 10-year history of compensated liver cirrhosis secondary to chronic hepatitis C infection. MRI demonstrated classical findings, including recanalized umbilical vein and esophageal varices (Figure 1, Figure 2). Causes and Etiology of Liver Cirrhosis Liver cirrhosis develops from progressive hepatocellular injury, leading to fibrosis and nodular regeneration. Key etiologies include: Viral hepatitis : Chronic hepatitis B and C are the most common global causes. Alcohol-related liver disease : Chronic excessive alcohol intake remains a leading factor. Non-alcoholic steatohepatitis (NASH) : Increasingly p...