Cerebral Venous Thrombosis (CVT): Causes, Pathophysiology, Clinical Presentation, Imaging, Treatment, and Prognosis
Cerebral Venous Thrombosis (CVT): Causes, Pathophysiology, Clinical Presentation, Imaging, Treatment, and Prognosis Introduction Cerebral venous thrombosis (CVT) is an uncommon yet potentially life-threatening cerebrovascular disorder characterized by thrombotic occlusion of cortical veins and/or dural venous sinuses. Its protean clinical manifestations, diverse precipitating factors, and imaging variability frequently delay diagnosis, underscoring the need for a systematic, up-to-date approach to recognition and management. This expert guide synthesizes pathobiology, epidemiology, clinical features, imaging strategy, treatment, and prognosis—and anchors these principles with a real-world case to illustrate decision-making pitfalls and pearls. Case Vignette (Index Case) A 78-year-old man presented with altered mental status and a new-onset seizure occurring one week after a fall. An initial non-contrast head CT was performed on arrival. Subsequent MRI sequences—including susceptibility...