Amoebic Hepatitis Abscess
Amoebic Hepatitis Abscess Causes of Amoebic Hepatitis Abscess Amoebic hepatitis abscess is caused by Entamoeba histolytica , a protozoan parasite. The infection primarily occurs through the ingestion of cysts from contaminated food, water, or direct contact with fecal matter. This organism is the etiological agent of amoebiasis , which affects the gastrointestinal system. Amoebic liver abscess (ALA) is one of the most common extra-intestinal manifestations of Entamoeba histolytica infection. Pathogenesis and Pathophysiology The pathogenesis of amoebic hepatitis abscess begins when Entamoeba histolytica cysts are ingested and excyst in the small intestine. The trophozoites then invade the intestinal mucosa and may disseminate via the bloodstream to distant organs, including the liver. The liver is the most common site for the development of extra-intestinal amoebiasis, and the parasite typically reaches the liver through the portal venous circulation. Upon arrival in the...