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Tumefactive Demyelination: A Deceptive Lesion That Mimics Brain Tumor

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  Tumefactive Demyelination: A Deceptive Lesion That Mimics Brain Tumor Desmielinización tumefactiva: una lesión engañosa que imita un tumor cerebral 종양성 탈수초화: 뇌종양을 모방하는 기만적인 병변 Introduction: Tumor or Demyelinating Disease? When a mass-like lesion is identified in the central nervous system, radiologists often consider glioma, metastasis, or abscess high on the differential diagnosis list. However, some of these lesions represent tumefactive demyelination , a form of demyelinating disease that mimics neoplastic processes. In this article, we review a real clinical case and explore the pathophysiology, epidemiology, clinical features, imaging findings, treatment, and prognosis of tumefactive demyelination. Case Presentation: A 46-Year-Old Man with Slurred Speech and Facial Weakness A previously healthy 46-year-old man presented to the emergency department with progressively worsening slurred speech for 10 days, followed by right facial droop and numbness, which he noticed whil...