Radial Artery Thrombosis: Pathophysiology, Diagnosis, and Management of a Rare but Critical Vascular Complication
Abstract Radial artery thrombosis (RAT) is a rare but potentially devastating vascular event that can lead to digital ischemia, tissue necrosis, and loss of hand function. Although the condition is most frequently associated with iatrogenic injury during arterial cannulation or catheterization, it can also occur following illicit drug injection , trauma, or systemic hypercoagulable states. This article presents an in-depth review of the pathophysiology, epidemiology, imaging features, differential diagnosis, management strategies, and prognosis of radial artery thrombosis, supplemented by a clinical case of a 54-year-old man with cocaine-induced RAT , illustrated by diagnostic angiographic images. The review integrates the latest global literature and evidence-based management guidelines to provide comprehensive insights for clinicians and medical trainees preparing for licensing examinations. Case Presentation A 54-year-old male with a history of intravenous drug use , chronic ...