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Langerhans Cell Histiocytosis with Floating Teeth and Diabetes Insipidus: When Oral Symptoms Reveal a Multisystem Disease

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Clinical Hook A 37-year-old man visited a dental clinic because of persistent oral pain and loose teeth that had gradually worsened over one year. Four teeth had fallen out spontaneously during the previous six months without significant trauma. Initially, severe periodontal disease was suspected. However, another clue emerged. The patient also reported excessive thirst and frequent urination that had developed several months earlier. Laboratory evaluation demonstrated hypernatremia and dehydration, suggesting diabetes insipidus rather than uncontrolled diabetes mellitus. These seemingly unrelated findings transformed an ordinary dental consultation into a complex multidisciplinary investigation involving oral surgery, radiology, endocrinology, pathology, and medical oncology. Panoramic radiography revealed one of the most characteristic imaging signs in skeletal radiology—the classic "floating teeth" appearance produced by destructive osteolytic lesions involving the...