MediAI

Adult Intussusception: A Rare but Critical CT Diagnosis Every Clinician Should Recognize Imagine a previously healthy middle-aged man arriving at the emergency department with severe upper abdominal pain and nausea. Initial evaluation appears relatively unremarkable. Laboratory findings are nonspecific. Symptoms partially improve with conservative management. Then the pain returns. A repeat CT scan reveals one of radiology's most recognizable yet potentially deceptive imaging signs—the "Target Sign." What appears at first glance to be a transient bowel abnormality may actually conceal an underlying malignancy. This was precisely the situation encountered in a patient ultimately diagnosed with jejunojejunal intussusception caused by small bowel adenocarcinoma. For radiologists, emergency physicians, gastroenterologists, and surgeons, adult intussusception remains a fascinating yet clinically important diagnosis because it differs dramatically from the pediatric disease. Un...

  Abstract Intussusception is a critical gastrointestinal condition characterized by the telescoping of one bowel segment into another, often leading to obstruction, ischemia, and potential perforation. While predominantly observed in pediatric populations, adult intussusception represents a diagnostically challenging and clinically significant entity, frequently associated with a pathological lead point such as malignancy. This article provides a comprehensive, expert-level review of intussusception, integrating clinical insights from a real-world case involving a 54-year-old male patient. Emphasis is placed on pathophysiology, epidemiology, clinical presentation, imaging features, differential diagnosis, diagnostic strategies, treatment modalities, and prognosis. Additionally, radiologic interpretation of CT imaging—including the hallmark “target sign”—is explored in depth.  Keywords Intussusception, Intussusception CT target sign, Adult intussusception diagnosis, Intus...

  Meckel's Diverticulum , the most prevalent congenital anomaly of the gastrointestinal tract, remains a "great masquerader" in clinical practice. Often asymptomatic, it can present with life-threatening complications such as massive gastrointestinal bleeding, intussusception, or diverticulitis, mimicking acute appendicitis. This column explores the intricate details of Meckel's Diverticulum diagnosis , Meckel's Diverticulum treatment , and the latest imaging modalities used to identify this vestigial remnant. Pathophysiology of Meckel's Diverticulum Meckel's Diverticulum arises from the incomplete obliteration of the vitelline duct (also known as the omphalomesenteric duct) during the fifth to seventh weeks of gestation. In normal embryonic development, this duct connects the primitive midgut to the yolk sac and should spontaneously involute. When this process fails, a "true diverticulum" is formed—meaning it contains all four layers of th...