Decoding May-Thurner Syndrome: A Comprehensive Guide to Iliac Vein Compression
May-Thurner Syndrome (MTS), also known as Iliac Vein Compression Syndrome or Cockett Syndrome, represents a critical, often underdiagnosed, vascular condition that is a significant predisposing factor for Deep Vein Thrombosis (DVT) in the lower extremities, particularly the left leg. This expert column, drawing on the latest international medical literature, provides a deep dive into the pathophysiology, clinical spectrum, diagnostic imaging, and modern endovascular management of MTS, offering essential knowledge for medical professionals and a detailed understanding for affected patients. Understanding May-Thurner Syndrome: A Critical Anatomical Variant May-Thurner Syndrome is a disorder caused by the extrinsic compression of a deep vein, most commonly the left common iliac vein (LCIV) , which is squeezed between the overlying right common iliac artery (RCIA) and the underlying fifth lumbar vertebral body or sacral promontory. This chronic mechanical irritation, coupled with the puls...