MediAI

  Introduction Uterine anomalies are a crucial aspect of reproductive medicine, often influencing fertility, pregnancy outcomes, and obstetric management. Among these, uterine didelphys, also known as a duplicated uterus, represents a rare Müllerian duct anomaly. This column will explore the cause, etiology, pathophysiology, epidemiology, clinical presentation, imaging features, treatment, and prognosis of uterine didelphys with intrauterine gestation, supported by imaging examples and case findings.  Etiology and Pathophysiology Uterine didelphys (duplicated uterus) is classified as a Class III Müllerian duct anomaly . It results from abnormal or failed fusion of the paramesonephric ducts (Müllerian ducts) during fetal development around the 8th to 9th weeks of gestation. Unlike a septate uterus, which arises from failed resorption of the medial septum, uterine didelphys is a true duplication anomaly, producing two completely separate uterine cavities, two endometrial ca...