MediAI

    Abstract Neurocysticercosis (NCC), caused by the larval stage of the Taenia solium tapeworm, remains the most prevalent parasitic infection of the human central nervous system (CNS) globally. While traditionally endemic in regions with poor sanitation across Latin America, Asia, and Africa, globalization and migration patterns have led to an increased incidence in developed nations. This article provides a high-level clinical synthesis of NCC, emphasizing its complex pathophysiology, diverse imaging features across different biological stages, and contemporary management strategies, including pharmacological and surgical interventions. I. Introduction Neurocysticercosis is recognized by the World Health Organization as a leading cause of acquired epilepsy in developing countries. The disease represents a significant public health challenge due to its chronic nature and the potential for severe neurological sequelae. Understanding the lifecycle of T. solium is cri...

  Introduction Neurocysticercosis (NCC) is the most common parasitic infection of the central nervous system worldwide , representing a leading cause of adult-onset seizures, particularly in endemic regions of Latin America, Sub-Saharan Africa, and Southeast Asia. With increasing globalization, immigration, and international travel, NCC has become a significant diagnostic consideration even in non-endemic developed countries. Despite being preventable, NCC continues to pose major diagnostic and therapeutic challenges due to its protean clinical manifestations, variable radiologic appearances, and complex host–parasite interactions. Advances in neuroimaging—especially MRI—have dramatically improved diagnostic accuracy, allowing earlier detection and targeted treatment strategies. This column provides an in-depth, expert-level review of neurocysticercosis, integrating pathophysiology, epidemiology, clinical manifestations, advanced imaging features, differential diagnosis, manag...