MediAI

Introduction: Why This Case Matters Renal angiomyolipoma (AML) is one of the most important renal manifestations of Tuberous Sclerosis Complex. Although often benign, AML can become life-threatening when it enlarges and develops abnormal blood vessels prone to rupture. The present case involves a 32-year-old woman with cognitive impairment and a history of seizures who demonstrated enlargement of a renal lesion on follow-up imaging. Magnetic resonance imaging (MRI) and ultrasound were performed to characterize the lesion and assess complications. The imaging findings were highly suggestive of TSC-associated renal AML.  From a radiology perspective, this case highlights several high-value topics: Multiorgan manifestations of TSC MRI characterization of fat-containing renal tumors Differential diagnosis between AML and renal cell carcinoma Bleeding risk assessment Integration of Medical Imaging AI and Clinical Decision Support Systems For healthcare executives and AI researchers, TSC...

  Perivascular Epithelioid Cell Tumor (PEComa): The Rare Tumor Every Radiologist Should Recognize Imagine a young patient arriving in the emergency department with nothing more alarming than a fever and a cough. A routine chest X-ray is performed. Instead of pneumonia alone, the radiologist discovers a large thoracic mass. Further CT imaging reveals a second renal lesion. Biopsy later confirms an exceptionally rare diagnosis: Perivascular Epithelioid Cell Tumor (PEComa). This scenario illustrates why PEComa matters in modern medical imaging , CT scan diagnosis , and radiology interpretation . Though uncommon, PEComa can mimic more common malignancies and may appear in the kidney, liver, mediastinum, uterus, lung, retroperitoneum, and soft tissues. For clinicians, radiologists, oncologists, and informed readers, understanding PEComa is increasingly important because targeted therapy using mTOR inhibitors has transformed treatment in selected patients. What Is Perivascular Epithelio...