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  Hyperostosis Frontalis Interna in a Breast Cancer Survivor: A Case-Based Nuclear Medicine Perspective Introduction Hyperostosis frontalis interna (HFI) is a benign, often incidental radiological finding characterized by excessive bone formation along the inner table of the frontal bone. Though it typically carries no clinical consequence, its radiologic features can mimic serious pathology, particularly in patients with a history of malignancy. In this case, a 43-year-old woman with a history of breast cancer , BRCA2 germline mutation, and prior chemotherapy presented with bilateral hip pain. Bone scintigraphy revealed findings consistent with HFI , raising important considerations in differential diagnosis and imaging interpretation. This blog post presents the full clinical and imaging analysis, diagnostic reasoning, key features of HFI, and concludes with a 10-question quiz to test your understanding, backed by references from SCI-grade literature. Case Summary Patient ...