MediAI

  Abstract Ogilvie’s syndrome, also known as acute colonic pseudo-obstruction (ACPO), is a rare but potentially life-threatening condition characterized by acute colonic dilatation in the absence of mechanical obstruction. This column presents a comprehensive, expert-level review integrating clinical case insights, imaging interpretation, and current global literature. Emphasis is placed on pathophysiology, epidemiology, diagnostic imaging, and evidence-based management strategies, structured in the format of a biomedical review. Keywords Ogilvie’s syndrome, acute colonic pseudo-obstruction, colonic dilatation, CT imaging, bowel obstruction, neostigmine, colonoscopic decompression I. Introduction Ogilvie’s syndrome is a critical gastrointestinal emergency that mimics mechanical bowel obstruction but lacks any obstructive lesion. First described by Sir William Ogilvie in 1948, this syndrome is increasingly recognized in hospitalized and critically ill patients. Failure to promptly ...