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Emergency Brain MRI: Recognizing PRES Before Permanent Neurological Injury

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  Introduction When Minutes Determine Whether Brain Injury Is Reversible A previously healthy 36-year-old woman suddenly developed a severe headache while at work. Within a short period, she experienced blurred vision, generalized tonic-clonic seizures, and progressive confusion. On arrival at the emergency department, her blood pressure exceeded 220/120 mmHg. The emergency physician immediately considered several neurological emergencies, including acute ischemic stroke, intracranial hemorrhage, cerebral venous thrombosis, encephalitis, and hypertensive encephalopathy. A non-contrast brain CT was rapidly performed. Although no intracranial hemorrhage was identified, subtle bilateral hypodense lesions were noted within the parieto-occipital white matter. These findings prompted immediate MRI evaluation. Magnetic Resonance Imaging demonstrated symmetric vasogenic edema involving both parieto-occipital lobes. Diffusion-weighted imaging revealed no evidence of restricted dif...