Marfan Syndrome and Ectopia Lentis: The Hidden MRI Finding Behind Progressive Vision Loss | Medical Imaging Guide.
Marfan Syndrome and Progressive Vision Loss: A Radiology Case Every Clinician Should Know A 33-year-old woman with a known history of Marfan syndrome presented with progressive bilateral visual loss over several months. Initially, her symptoms appeared to be primarily ophthalmologic. However, advanced medical imaging revealed a striking diagnosis: bilateral posterior lens dislocation (ectopia lentis). This case highlights the critical role of medical imaging, MRI interpretation, and multidisciplinary diagnosis in patients with connective tissue disorders. Although Marfan syndrome is widely recognized for its cardiovascular complications, radiologists frequently encounter imaging manifestations involving the eyes, skeleton, lungs, and vascular system. Understanding these findings is essential because early diagnosis can prevent irreversible visual impairment and life-threatening cardiovascular complications. Clinical Case Presentation A 33-year-old female with known Marfan syndrome pres...