Pediatric Ménétrier Disease: CT and Endoscopic Findings of Giant Gastric Folds in a 5-Year-Old Boy
Edited by ScholarGen MediAI Team Executive Answer Ménétrier disease is a rare protein-losing gastropathy characterized by markedly enlarged gastric rugal folds, typically involving the gastric body and fundus, with associated hypoalbuminemia and edema. In this 5-year-old boy, the combination of nausea, vomiting, intermittent abdominal pain, mild periorbital edema, severe hypoalbuminemia, and giant cerebriform gastric folds on contrast-enhanced CT and endoscopy strongly supports pediatric Ménétrier disease. Gastric biopsy demonstrated foveolar hyperplasia with glandular atrophy, while testing for Helicobacter pylori and viral inclusions was negative. Technetium-99m-labeled human serum albumin scintigraphy demonstrated gastrointestinal protein loss. The child improved with supportive treatment, with symptoms resolving four months after presentation. Why This Case Matters Pediatric Ménétrier disease is uncommon and can initially resemble a much more routine gastrointestinal illness...