MediAI

  Abstract Acute pulmonary embolism (PE) remains a significant cause of cardiovascular mortality worldwide. Early and accurate diagnosis is critical, yet the clinical presentation often mimics other cardiopulmonary pathologies. This article examines the pathophysiological mechanisms of PE, focusing on the classical but rare radiographic sign known as Hampton’s Hump . Through a clinical case analysis of a 47-year-old male presenting with pleuritic chest pain and hypoxia, we explore the integration of Chest X-ray (CXR) and Computed Tomography Angiography (CTA) in the diagnostic algorithm. We further delineate the epidemiology, clinical manifestations, and evidence-based treatment protocols essential for biomedical engineering applications and clinical practice. I. Introduction Pulmonary embolism (PE) is a life-threatening condition characterized by the occlusion of one or more pulmonary arteries by thrombi originating from distant sites, typically the deep veins of the lower ext...