MediAI

  Abstract Osteomalacia is a metabolic bone disease characterized by defective bone mineralization in adults, primarily caused by vitamin D deficiency, impaired phosphate metabolism, or disorders affecting bone matrix mineralization. In recent years, artificial intelligence (AI)–assisted diagnostic systems, combined with advanced imaging and biochemical analytics, have significantly improved early detection and treatment outcomes. This column presents a comprehensive AI-based clinical review of Osteomalacia diagnosis and treatment, integrating pathophysiology, epidemiology, clinical presentation, imaging features, differential diagnosis, treatment strategies, and prognosis. The discussion is structured to show that machine learning in musculoskeletal radiology can enhance diagnostic accuracy and patient care. Keywords— Osteomalacia, Osteomalacia diagnosis, Osteomalacia treatment, AI medical imaging, metabolic bone disease, vitamin D deficiency, Looser zones, stress fractures I....