Crohn Disease-Associated Small Bowel Adenocarcinoma: CT and MRI Findings of a Duodenal Cancer with Liver Metastasis
Edited by ScholarGen MediAI Team A radiologic approach to asymmetric bowel-wall thickening, obstruction, lymphadenopathy, and metastatic disease in Crohn disease Executive Answer Small bowel adenocarcinoma is an uncommon but clinically important malignancy in patients with Crohn disease. The diagnostic challenge is that its symptoms and imaging appearance can overlap with active inflammation or fibrostenotic Crohn disease. In this case, a man in his late 30s presented with abdominal pain and vomiting. CT demonstrated focal asymmetric duodenal wall thickening with regional lymphadenopathy and a separate low-attenuation liver lesion. MRI demonstrated abnormal bowel-wall thickening and diffusion restriction, with a corresponding abnormal liver lesion. Biopsy established poorly differentiated adenocarcinoma in the duodenum and moderately differentiated adenocarcinoma in the liver, consistent with metastatic small bowel adenocarcinoma. The central imaging lesson is simple: a new, foca...