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Crohn Disease-Associated Small Bowel Adenocarcinoma: CT and MRI Findings of a Duodenal Cancer with Liver Metastasis

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  Edited by ScholarGen MediAI Team A radiologic approach to asymmetric bowel-wall thickening, obstruction, lymphadenopathy, and metastatic disease in Crohn disease Executive Answer Small bowel adenocarcinoma is an uncommon but clinically important malignancy in patients with Crohn disease. The diagnostic challenge is that its symptoms and imaging appearance can overlap with active inflammation or fibrostenotic Crohn disease. In this case, a man in his late 30s presented with abdominal pain and vomiting. CT demonstrated focal asymmetric duodenal wall thickening with regional lymphadenopathy and a separate low-attenuation liver lesion. MRI demonstrated abnormal bowel-wall thickening and diffusion restriction, with a corresponding abnormal liver lesion. Biopsy established poorly differentiated adenocarcinoma in the duodenum and moderately differentiated adenocarcinoma in the liver, consistent with metastatic small bowel adenocarcinoma. The central imaging lesson is simple: a new, foca...

Acute Appendicitis on CT: The Mural Defect That May Signal Microperforation

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Edited by ScholarGen MediAI Team Executive Answer Acute appendicitis is diagnosed on CT by integrating appendiceal enlargement with mural thickening, wall enhancement, and periappendiceal inflammatory change. In this adolescent female case, the appendix was markedly dilated to approximately 16 mm and demonstrated mural thickening, enhancement, extensive surrounding fat stranding, adjacent fluid, and a focal mural defect. The mural defect is particularly important because it raises concern for necrosis and microperforation, moving the interpretation beyond uncomplicated appendicitis. For radiologists, the key lesson is simple: do not stop after identifying an enlarged appendix. Evaluate the appendiceal wall, surrounding tissues, fluid, gas, and alternative diagnoses systematically. Why This Case Matters Acute abdominal pain in an adolescent can present a diagnostic challenge because several gastrointestinal, urinary, and gynecologic conditions can produce similar symptoms. When right lo...

Adrenal Myelolipoma in a Patient With Metastatic Neuroendocrine Tumor: The CT Finding That Prevents a False Diagnosis of Adrenal Metastasis

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Edited by ScholarGen MediAI Team Executive Answer An adrenal mass in a patient with known metastatic malignancy is not automatically an adrenal metastasis. In this case, a well-defined left adrenal mass measured approximately −59 HU on CT , strongly indicating macroscopic fat. MRI further demonstrated persistent high signal on in-phase and out-of-phase images with signal suppression on fat-suppressed sequences, supporting macroscopic rather than intracellular lipid. Diffusion-weighted imaging showed no definite restriction, and the lesion demonstrated no significant uptake on Cu-64 DOTATATE PET/CT. Taken together, these findings support adrenal myelolipoma , a benign fat-containing adrenal tumor, rather than metastatic neuroendocrine tumor. Why This Case Matters An adrenal mass can become diagnostically difficult when it appears in a patient who already has proven malignancy. The clinical context can create a powerful assumption: Known cancer + new adrenal mass = adrenal metastasis. Th...