Silicosis With Progressive Massive Fibrosis: A Radiologist’s Guide to Dyspnea, Chest CT, and Occupational Exposure
Edited by ScholarGen MediAI Team Executive Clinical Summary A man in his 60s presented with progressively worsening dyspnea. Chest radiography demonstrated bilateral upper-lung predominant mass-like opacities accompanied by numerous small nodular opacities. Calcified hilar and mediastinal lymph nodes provided an additional diagnostic clue. His occupational history revealed previous sandblasting exposure. Chest CT subsequently demonstrated large, confluent, partially calcified masses predominantly involving the upper lungs, extensive small pulmonary nodules with a perilymphatic distribution, and enlarged partially calcified hilar and mediastinal lymph nodes. Taken together, the clinical and radiologic pattern is highly characteristic of silicosis with progressive massive fibrosis (PMF) . The diagnostic lesson is broader than recognizing a large fibrotic mass. A radiologist must integrate the distribution of pulmonary nodules, the morphology and location of the fibrotic masses, lym...