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Brain Capillary Telangiectasia: CT Calcification, MRI Enhancement, SWI Susceptibility, and the Critical Differential Diagnosis

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Edited by ScholarGen MesiAI Team Executive Clinical Summary A woman in her 60s with a long history of headache underwent brain CT because her headaches had recently become more frequent. Neurologic examination revealed no specific abnormality. CT unexpectedly demonstrated a focal coarse calcification in the medial right inferior temporal region. At first glance, an intra-axial calcified lesion can raise a broad differential diagnosis, including previous infection, congenital abnormalities, vascular malformation, and chronic blood products or post-traumatic change. However, calcification itself is not a diagnosis. The critical diagnostic step is to correlate the CT finding with multiparametric MRI. In this case, MRI demonstrated a small enhancing lesion without a significant surrounding FLAIR abnormality, without diffusion restriction, and without a prominent T2 flow void. MRA showed no major high-flow vascular abnormality. Susceptibility-sensitive imaging provided an additional vascula...

Silicosis With Progressive Massive Fibrosis: A Radiologist’s Guide to Dyspnea, Chest CT, and Occupational Exposure

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  Edited by ScholarGen MediAI Team Executive Clinical Summary A man in his 60s presented with progressively worsening dyspnea. Chest radiography demonstrated bilateral upper-lung predominant mass-like opacities accompanied by numerous small nodular opacities. Calcified hilar and mediastinal lymph nodes provided an additional diagnostic clue. His occupational history revealed previous sandblasting exposure. Chest CT subsequently demonstrated large, confluent, partially calcified masses predominantly involving the upper lungs, extensive small pulmonary nodules with a perilymphatic distribution, and enlarged partially calcified hilar and mediastinal lymph nodes. Taken together, the clinical and radiologic pattern is highly characteristic of silicosis with progressive massive fibrosis (PMF) . The diagnostic lesson is broader than recognizing a large fibrotic mass. A radiologist must integrate the distribution of pulmonary nodules, the morphology and location of the fibrotic masses, lym...