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Diagnosing Intestinal Angioedema on MDCT: A Radiologist's Guide to Mimics of Acute Abdomen

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  Executive Clinical Summary Recurrent acute abdominal pain without a clear etiology poses a diagnostic challenge in emergency departments and outpatient clinics. When conventional laboratory markers and physical examinations fail to yield a definitive diagnosis, radiologists and clinicians must consider non-mechanical, fluid-mediated causes of bowel wall thickening. Intestinal angioedema is a distinct, often underdiagnosed clinical entity characterized by localized, transient submucosal edema of the gastrointestinal tract. This condition can mimic acute surgical abdomen, leading to unnecessary exploratory laparotomies if imaging findings are misread. This article provides an in-depth analysis of the clinical presentation, multidetector computed tomography (MDCT) diagnostic features, underlying pathophysiology, differential diagnoses, and enterprise healthcare workflow integration for intestinal angioedema. Key Clinical Questions What are the characteristic MDCT imaging features t...