MediAI

Introduction Desmoid-type aggressive fibromatosis (AF), also known as desmoid tumor, is a rare, fibroblastic, locally invasive neoplasm with no metastatic potential but with a high recurrence rate. Although histologically benign, it often behaves aggressively by infiltrating surrounding structures, leading to significant morbidity. Among the extra-abdominal forms, the gluteal region is a recognized but relatively uncommon site. This article  offers an expert-level review of  gluteal desmoid-type aggressive fibromatosis , with a focus on its cause, etiology, pathophysiology, epidemiology, clinical presentation, imaging features, treatment options , and prognosis. All imaging findings are directly referenced from the provided case study of a 42-year-old woman with swelling in the right gluteal area. Cause and Etiology The etiology of desmoid-type fibromatosis is multifactorial and involves both genetic and environmental influences. 1.     Genetic...