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Showing posts from September, 2025

Delayed Onset Muscle Soreness (DOMS) after Hamstring Injury: Pathophysiology, Imaging Insights, Diagnosis, and Treatment

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Introduction Delayed onset muscle soreness (DOMS) represents a common yet clinically significant phenomenon encountered in sports medicine, musculoskeletal radiology, rehabilitation, and orthopedics. While DOMS is typically self-limiting, its manifestation following hamstring injury poses diagnostic challenges because its symptoms overlap with partial muscle tears, hematomas, or myotendinous junction injuries. In this post, we present an in-depth discussion of DOMS following hamstring injury, anchored on the case of a 31-year-old male with right hamstring pain . Using the latest global evidence and imaging findings, this column will explore DOMS from pathophysiology to prognosis , highlighting the role of magnetic resonance imaging (MRI) and evidence-based treatment strategies. Pathophysiology DOMS after hamstring injury is primarily associated with eccentric contractions during running, sprinting, or resistance training. The mechanisms include: Microscopic myofibrillar di...

Clinical Significance and Imaging Findings of Left Superior Vena Cava Draining into Right Superior Vena Cava

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  1. Introduction The left superior vena cava (LSVC) is among the most common thoracic venous anomalies, reported in approximately 0.3–0.5% of the general population. Normally, the right superior vena cava (RSVC) serves as the principal venous channel, directing deoxygenated blood from the head and upper extremities into the right atrium. However, due to embryologic variations, a persistent left-sided superior vena cava may remain. In most cases, the LSVC drains into the coronary sinus, typically without clinical consequences. In some patients, however, anomalous drainage into the left atrium or, as in this case, into the right superior vena cava may occur. Such variations, if unrecognized, may lead to complications during cardiac catheterization, central venous line placement, cardiac surgery, or pacemaker lead insertion. This case demonstrates a rare anomaly in which the LSVC courses inferior to the aortic arch and drains directly into the RSVC — a highly unusual pattern scarc...

Urinary Retention: Pathophysiology, Clinical Imaging Features, and Evidence-Based Management

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 Introduction Urinary retention is a urological condition characterized by the inability to voluntarily empty the bladder completely.  It represents a significant cause of morbidity across diverse populations and remains a clinical entity of high relevance in both acute and chronic settings.  With the aging global population and the rising prevalence of comorbid conditions such as diabetes mellitus and neurological disorders, urinary retention continues to be a crucial area of research and clinical focus. In this comprehensive column, we will review the pathophysiology, epidemiology, clinical presentation, imaging findings, differential diagnosis, diagnostic strategies, treatment modalities, and prognosis of urinary retention.   The discussion will integrate state-of-the-art imaging features illustrated by clinical cases, including CT and ultrasound, provided in the case review file.  1. Pathophysiology of Urinary Retention Urinary retention occurs whe...

Cerebral Schistosomiasis: Pathophysiology, Imaging, Diagnosis, and Treatment – A Comprehensive Case-Based Review

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Introduction Cerebral schistosomiasis is a rare but clinically significant manifestation of Schistosoma infection , a parasitic disease that affects over 250 million people worldwide.  While schistosomiasis typically involves the urogenital or hepatointestinal systems, neurological involvement—known as neuroschistosomiasis —can result in severe complications, including seizures, focal neurological deficits, and cognitive impairment. This article presents an in-depth analysis of cerebral schistosomiasis, drawing from a real case of a 33-year-old man who developed seizures and confusion after returning from São Tomé and Príncipe.  The discussion integrates the latest global literature on pathophysiology, epidemiology, clinical presentation, imaging features, differential diagnosis, treatment, and prognosis. Case Presentation A 33-year-old Caucasian male presented with severe headaches, focal seizures, and confusion three weeks after returning from São Tomé and Príncipe...

Ewing Sarcoma: Pathophysiology, Imaging Features, Diagnosis, and Treatment – A Comprehensive Review

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Ewing sarcoma is one of the most aggressive and clinically challenging malignant bone tumors affecting children and young adults. This column provides a comprehensive review of Ewing sarcoma , focusing on its pathophysiology, epidemiology, clinical presentation, imaging features, differential diagnosis, treatment, and prognosis , supported by leading literature. The case study and imaging examples included here will serve as both a clinical guide and an educational resource for medical students, radiology residents, and oncology specialists. Case Presentation A 13-year-old girl presented with several months of left chest wall pain . She underwent chest radiography and CT imaging. The findings are discussed below. History and Radiography Patient : 13-year-old female Symptom : Persistent left chest wall pain Figure 1. Chest Radiograph (P-A View). Interpretation: Expansile lesion involving the anterior portion of the 4th left rib. No evidence of pneumothorax or significant p...