Recurrent Tracheobronchial Papillomatosis with Pulmonary Involvement due to HPV Types 6 and 11
Recurrent Tracheobronchial Papillomatosis with Pulmonary Involvement due to HPV Types 6 and 11 Introduction Recurrent tracheobronchial papillomatosis with pulmonary involvement is a rare but serious manifestation of juvenile recurrent respiratory papillomatosis (JORRP) caused by HPV 6 and HPV 11. Integrating CT imaging correlation, viral genotype analysis, and clinical management, this case reflects the potential for lower airway and lung disease in HPV 6/11 infection, often underestimated. Drawing upon the case report “17-year-old male with juvenile recurrent respiratory papillomatosis” from Applied Radiology (July 2011), this case exemplifies disease progression from cervical/tracheal papillomas to pulmonary cavitary lesions, nodules, and bronchial obstruction, despite prior surgical and antiviral (cidofovir) therapy 1. Clinical Background A 17‑year‑old male with a long history of juvenile‑onset RRP began experiencing exacerbation of cough and dyspnea , despite multip...