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Showing posts with the label portal hypertension

Liver Cirrhosis: Comprehensive Review of Causes, Pathophysiology, Diagnosis, and Management Strategies.

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Introduction Liver cirrhosis represents the terminal stage of chronic liver disease and remains a significant cause of morbidity and mortality worldwide. This blog column aims to provide a globally optimized, expert-level overview of liver cirrhosis, integrating the latest evidence-based practices.  Case A 72-year-old female presented with lower extremity edema and had a 10-year history of compensated liver cirrhosis secondary to chronic hepatitis C infection. MRI demonstrated classical findings, including recanalized umbilical vein and esophageal varices (Figure 1, Figure 2). Causes and Etiology of Liver Cirrhosis Liver cirrhosis develops from progressive hepatocellular injury, leading to fibrosis and nodular regeneration. Key etiologies include: Viral hepatitis : Chronic hepatitis B and C are the most common global causes. Alcohol-related liver disease : Chronic excessive alcohol intake remains a leading factor. Non-alcoholic steatohepatitis (NASH) : Increasingly p...

Understanding Splenic Vein Thrombosis: A Comprehensive Clinical and Radiologic Insight

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  Understanding Splenic Vein Thrombosis: A Comprehensive Clinical and Radiologic Insight Introduction Splenic vein thrombosis (SVT) is an uncommon yet clinically important vascular disorder that is frequently overlooked in routine practice. Most cases are closely linked to underlying pancreatic diseases, particularly pancreatitis. Early and accurate recognition is essential, especially in patients who present with unexplained splenomegaly or signs of upper gastrointestinal bleeding. This in-depth article provides a comprehensive, expert-level review of SVT, covering its etiology, pathophysiology, epidemiological trends, clinical manifestations, diagnostic imaging features, treatment approaches, and long-term prognosis. It is designed as a valuable resource for radiologists, gastroenterologists, and other healthcare professionals involved in abdominal and vascular diagnostics. What Is Splenic Vein Thrombosis? Splenic vein thrombosis refers to the formation of a blood clot with...