MediAI

https://doi.org/10.1056/NEJMicm1403124 Introduction: Understanding Trichobezoar in Clinical Practice Trichobezoar, commonly referred to as a hair bezoar, is a rare but clinically significant gastrointestinal condition characterized by the accumulation of ingested hair within the stomach and sometimes extending into the small intestine. This condition is strongly associated with psychiatric disorders such as trichotillomania and trichophagia, making it a fascinating intersection between gastroenterology, radiology, and psychiatry.  This column provides a comprehensive, expert-level yet reader-friendly analysis of trichobezoar, integrating real case imaging findings, pathophysiology, and diagnosis. https://doi.org/10.4021/gr2008.11.1287 Case Overview: 18-Year-Old Female with Abdominal Pain and Vomiting An 17-year-old female with a known history of autism and trichotillomania presented with: Persistent vomiting for 48 hours Abdominal pain Normal vital signs and laboratory findings Im...

  Abstract Corkscrew esophagus, classically associated with Diffuse Esophageal Spasm (DES), represents a rare but clinically significant esophageal motility disorder characterized by uncoordinated, high-amplitude contractions of the distal esophagus. This condition produces the hallmark radiologic appearance of a “corkscrew” or “rosary bead” esophagus on contrast esophagography. Despite its rarity, corkscrew esophagus remains a critical diagnostic consideration in patients presenting with intermittent dysphagia and non-cardiac chest pain. This column provides a comprehensive, expert-level review of corkscrew esophagus, including pathophysiology, epidemiology, clinical presentation, imaging findings, differential diagnosis, diagnostic modalities, treatment strategies, and prognosis, grounded in the latest global literature. A real-world case is presented with imaging correlation, followed by examination-style questions to reinforce learning. Keywords Corkscrew Esophagus, Diff...