Advanced Diagnostic and Therapeutic Frameworks in Neurocysticercosis: A Comprehensive Review of Clinical Pathophysiology and Neuroimaging
Abstract Neurocysticercosis (NCC), caused by the larval stage of the Taenia solium tapeworm, remains the most prevalent parasitic infection of the human central nervous system (CNS) globally. While traditionally endemic in regions with poor sanitation across Latin America, Asia, and Africa, globalization and migration patterns have led to an increased incidence in developed nations. This article provides a high-level clinical synthesis of NCC, emphasizing its complex pathophysiology, diverse imaging features across different biological stages, and contemporary management strategies, including pharmacological and surgical interventions. I. Introduction Neurocysticercosis is recognized by the World Health Organization as a leading cause of acquired epilepsy in developing countries. The disease represents a significant public health challenge due to its chronic nature and the potential for severe neurological sequelae. Understanding the lifecycle of T. solium is cri...