MediAI

https://doi.org/10.1056/NEJMicm1403124 Introduction: Understanding Trichobezoar in Clinical Practice Trichobezoar, commonly referred to as a hair bezoar, is a rare but clinically significant gastrointestinal condition characterized by the accumulation of ingested hair within the stomach and sometimes extending into the small intestine. This condition is strongly associated with psychiatric disorders such as trichotillomania and trichophagia, making it a fascinating intersection between gastroenterology, radiology, and psychiatry.  This column provides a comprehensive, expert-level yet reader-friendly analysis of trichobezoar, integrating real case imaging findings, pathophysiology, and diagnosis. https://doi.org/10.4021/gr2008.11.1287 Case Overview: 18-Year-Old Female with Abdominal Pain and Vomiting An 17-year-old female with a known history of autism and trichotillomania presented with: Persistent vomiting for 48 hours Abdominal pain Normal vital signs and laboratory findings Im...

  Abstract Intussusception is a critical gastrointestinal condition characterized by the telescoping of one bowel segment into another, often leading to obstruction, ischemia, and potential perforation. While predominantly observed in pediatric populations, adult intussusception represents a diagnostically challenging and clinically significant entity, frequently associated with a pathological lead point such as malignancy. This article provides a comprehensive, expert-level review of intussusception, integrating clinical insights from a real-world case involving a 54-year-old male patient. Emphasis is placed on pathophysiology, epidemiology, clinical presentation, imaging features, differential diagnosis, diagnostic strategies, treatment modalities, and prognosis. Additionally, radiologic interpretation of CT imaging—including the hallmark “target sign”—is explored in depth.  Keywords Intussusception, Intussusception CT target sign, Adult intussusception diagnosis, Intus...

  Abstract Corkscrew esophagus, classically associated with Diffuse Esophageal Spasm (DES), represents a rare but clinically significant esophageal motility disorder characterized by uncoordinated, high-amplitude contractions of the distal esophagus. This condition produces the hallmark radiologic appearance of a “corkscrew” or “rosary bead” esophagus on contrast esophagography. Despite its rarity, corkscrew esophagus remains a critical diagnostic consideration in patients presenting with intermittent dysphagia and non-cardiac chest pain. This column provides a comprehensive, expert-level review of corkscrew esophagus, including pathophysiology, epidemiology, clinical presentation, imaging findings, differential diagnosis, diagnostic modalities, treatment strategies, and prognosis, grounded in the latest global literature. A real-world case is presented with imaging correlation, followed by examination-style questions to reinforce learning. Keywords Corkscrew Esophagus, Diff...

  Keywords: stroke, acute ischemic stroke, stroke imaging, CT stroke diagnosis, middle cerebral artery stroke, anterior circulation infarction, stroke pathophysiology, stroke treatment Abstract Stroke remains one of the most devastating neurological disorders worldwide and represents a leading cause of mortality and long-term disability. Early diagnosis using neuroimaging—especially computed tomography (CT)—plays a critical role in determining therapeutic strategies and improving clinical outcomes. This article presents an in-depth expert analysis of acute ischemic stroke in the anterior circulation , integrating clinical history, imaging interpretation, pathophysiology, epidemiology, diagnosis, treatment, and prognosis. The discussion is based on the clinical imaging case described in the attached material and supported by the latest evidence from internationally recognized literature such as the World Health Organization , American Heart Association , and the National Institu...