Radiation Pneumonitis After Breast Cancer Radiotherapy: CT Imaging Findings, Differential Diagnosis, Treatment, and Prognosis
Clinical Hook A 55-year-old woman presents to the emergency department with persistent cough, fever, and dyspnea several weeks after treatment for breast cancer. At first glance, the clinical presentation may suggest ordinary pneumonia. But the chest CT tells a different story. Instead of a random or bronchocentric pulmonary opacity, the abnormality is concentrated in the portion of the right lung corresponding to the radiation treatment field, with ground-glass opacity, interstitial change, architectural distortion, and localized volume loss. This is the imaging pattern that should immediately raise the possibility of radiation pneumonitis . The case provided for this review describes a 55-year-old woman with invasive ductal carcinoma of the right breast who underwent breast-conserving surgery, regional radiotherapy, and chemotherapy. Four weeks after treatment, she developed persistent cough, fever, and dyspnea. CT demonstrated abnormalities in the right upper lung corresponding to t...