MediAI

  Testicular Epidermoid Cyst: Causes, Diagnosis, Imaging, Treatment, and Prognosis Introduction Testicular epidermoid cysts (TECs) are rare, benign intratesticular lesions that can clinically and radiologically mimic malignant germ cell tumors. Despite their benign nature, accurate diagnosis is critical because radical orchiectomy is often performed due to diagnostic uncertainty. TECs account for approximately 1–2% of all testicular tumors and are composed entirely of keratinizing squamous epithelium without any dermal appendages. Their etiology remains controversial, but their characteristic imaging appearance—particularly on ultrasound—can aid in diagnosis and avoid unnecessary aggressive treatment. 1. Cause and Etiology The exact cause of testicular epidermoid cysts is not fully understood. Two prevailing theories exist: Monodermal Teratoma Theory TECs may represent a monodermal variant of mature teratomas derived from germ cells that differentiate exclusively into ker...