MediAI

Introduction Non-specific interstitial pneumonia (NSIP) is a distinctive form of idiopathic interstitial pneumonia (IIP) that has drawn increasing global attention due to its overlapping features with other diffuse parenchymal lung diseases. Unlike usual interstitial pneumonia (UIP), NSIP is characterized by temporally uniform inflammation and fibrosis, presenting unique diagnostic and therapeutic challenges. This comprehensive article explores the pathophysiology, epidemiology, clinical presentation, imaging features, differential diagnosis, diagnostic approaches, treatment strategies, and prognosis of NSIP.  The review is grounded in recent literature, including pivotal studies from The New England Journal of Medicine, Lancet Respiratory Medicine, Radiology, and American Journal of Respiratory and Critical Care Medicine. Pathophysiology NSIP is primarily characterized by chronic interstitial inflammation and varying degrees of fibrosis. Unlike UIP, which displays spatial an...

  Chronic Eosinophilic Pneumonia Neumonía eosinofílica crónica 만성 호산구성 폐렴 Keywords: chronic eosinophilic pneumonia, peripheral airspace opacities, photographic negative, eosinophilia, prednisone, CT scan, allergic asthma, corticosteroid response Introduction Chronic eosinophilic pneumonia (CEP) is a rare but distinct form of idiopathic interstitial lung disease characterized by prominent pulmonary and peripheral eosinophilic infiltration.  Often affecting middle-aged women with a history of asthma or atopy, it presents insidiously with systemic symptoms that mimic more common pulmonary infections or malignancies.  A hallmark radiological feature, described as the “imaging negative of pulmonary edema,” provides a vital diagnostic clue and has been consistently associated with CEP.  This case-based discussion outlines the pathogenesis, clinical and imaging characteristics, diagnosis, and treatment of CEP. Case Summary A 54-year-old woman with known allergic rhi...